Senior Scientist I/II, HSC Therapies

At Editas Medicine, we are pioneering the possible. Our mission and commitment is to translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world.  Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases.  

Why Choose Editas?

At Editas Medicine, we’re a team of passionate problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor!

Decoding The Role:

As a Senior Scientist I/II, you’ll be a vital contributor to our mission and our success, contributing to our understanding of hematopoietic stem cell biology, helping to drive innovative research aimed at transforming the treatment landscape for non-malignant hematopoietic stem cell diseases. Leveraging your expertise, you will contribute to our in vivo genome editing pipeline, working to uncover novel insights into HSC development and disease mechanisms, directly impacting the identification and development of groundbreaking therapies. You will actively participate in research teams and collaborate effectively across functions to meet timeline sensitive goals while maintaining high quality output.

Characterizing Your Impact:

As a Senior Scientist I/II, you will:

• Design and conduct in vivo and in vitro experiments to elucidate the mechanisms of hematopoietic stem cell development and disease.
• Support discovery effort for in vivo HSC editing approach for β-hemoglobinopathies and other non-malignant HSC diseases.
• Support project strategy development, manage research timeline and deliverables, plan, and coordinate project work with functional stakeholders.
• Serve as a technical and scientific resource for Associate Scientists to perform research supporting development of HSC-based therapies from early discovery to regulatory filing.
• Establish SOPs, write prospective protocols, author study reports and regulatory documents, assist patent filing, and contribute to business development activities. 
• Maintain detailed record electronically in accordance with Editas’ policy, analyze data and present at internal and external meetings.
• Manage interactions with vendors, CROs, KOLs, and academic collaborators. 

Requirements

The Ideal Transcript:

To thrive in this role, you’ll need:

Qualifications:

• Ph.D in developmental biology, cell and molecular biology or a related field, with minimum of 5 years of working experience in the field of hematopoietic stem cell biology, including strong publication records.
• Solid understanding of hematopoietic stem cell biology, red cell biology and disease pathogenesis is required.
• Must have hands-on experience working with mouse models, writing/managing animal protocols and is proficient in dosing, tissue harvest, and processing.
• Must be proficient in cell-based assay development and molecular techniques.
• Ability to conduct high-quality research, execute research plans in a timely and organized manner and effectively communicate progress to cross-functional team

Fundamentals That Set You Apart

• Hands-on experience with gene editing technologies is a plus.
• Hands-on experience in development of gene and cell therapy in pharmaceutical and/or biotechnology industry is desirable.
• Working experience with lipid nanoparticles for targeted delivery in vivo is highly desired.
• Ability to think critically, synthesize and extract simple principles from complex datasets, communicate effectively across broad spectrum of audience both internal and external to Editas

Benefits

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

Aspire to be an Editor? We invite you to apply and join us at the forefront of innovation and be a key contributor to realizing Editas Medicine's mission of developing transformative medicines for people living with serious diseases..